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Pathology and Genetics of Tumours of Endocrine Organs The International Agency for Research on Cancer
Publisher: World Health Organization

In WHO Classification of Tumours . Because the genes that cause these genetic syndromes are known, scientists can understand the cellular pathways which lead to the development of pancreatic endocrine neoplasms. All results were hormone and sex dependent, and the pathological pro-files were comparable. This volume covers tumors of the pituary, the thyroid and parathyroid, the adrenal gland, the endocrine pancreas, and inherited tumor syndromes. Careful pathological examination of such pancreatic resection specimen is also recommended as very small tumors can cause obstructive pancreatitis. DeLellis RA, Lloyd RD, Heitz PU, Eng C: WHO: Pathology and Genetics. The International Agency for Research on Cancer. In: DeLellis RA, Lloyd RV, Heitz PU, Eng C, editor. Edited by: Kleihues P and Sobin LE. Lyon, France, IARC Press; 2004. World health organization classification of tumours pathology and genetics of tumours of endocrine organs. The hope is that a Patients with von Hippel-Lindau are predisposed to developing tumors in a number of organs including the the brain (hemagioblastoma), the eye (hemagioblastoma), the kidney (renal cell carcinoma), and the adrenals (pheochromocytoma). Pathology.and.Genetics.of.Tumours.of.Endocrine. Several clinical trials target PI3K/Akt/mTOR signaling; however, it is unknown whether these or other genes are genetically altered in these tumors. Pathology and Genetics of Tumours of Endocrine Organs.